Tag: Genome

Free Download Models and Algorithms for Genome Evolution By Chauve, Cedric;El-Mabrouk, Nadia;Tannier, Eric
2013 | 328 Pages | ISBN: 1447152980 | EPUB | 3 MB
Part I: Emergence of Standard Algorithms — What’s Behind Blast — Forty Years of Model-Based Phylogeography — How to Infer Ancestral Genome Features by Parsimony — Duplication, Rearrangement and Reconciliation — The Genesis of the DCJ Formula — Part II: New Lights on Current Paradigms — Large-Scale Multiple Sequence Alignment and Phylogeny Estimation — Rearrangements in Phylogenetic Inference — Status of Research on Insertion and Deletion Variations in the Human Population — A Retrospective on Genomic Preprocessing for Comparative Genomics — A Comparison of DCJ and Algebraic Distances — Part III: Promising Directions — Fractionation, Rearrangement, Consolidation, Reconstruction — Error Detection and Correction of Gene Trees — The Potential of Family-Free Genome Comparison — Genetic History of Populations.

Free Download A Roadmap for Plant Genome Editing by Agnès Ricroch, Dennis Eriksson, Dragana Miladinović, Jeremy Sweet, Katrijn Van Laere, Ewa Woźniak-Gientka
English | PDF EPUB (True) | 2023 (2024 Edition) | 546 Pages | ISBN : 3031461495 | 34.1 MB
This book is an update of genome editing techniques applied to a range of plants. We discuss the latest techniques and applications to cereals, roots and tubers, oilseed crops, fruit and forest trees, vegetables, legumes and algae including resistance to biotic and abiotic stresses, improved quality, drug production, yield and adaptation to climate change. The regulations in different countries worldwide, the patentibility and the perception by society of the applications of new genomic techniques are examined. This book is written by a multidisciplinary and multisectoral collective of high-profile scientists and other experts belonging to the COST Action network PlantEd, which is mainly European but with contributions from American, Australian, Canadian, Chinese, Indian, Iranian, Pakistani and Peruvian scientists. The book is aimed at a wide audience consisting of students, academics, private and public breeders, other actors in the food and bioeconomy value chains and policy and law makers.

Free Download Compendium of Crop Genome Designing for Nutraceuticals
English | 2023 | ISBN: 9811941688 | 2943 Pages | PDF EPUB (True) | 100 MB
The crop plants cater not only to our basic F5 (food, feed, fiber, fuel, and furniture) needs but also provide a number of nutraceuticals with potential nutritional, safety and therapeutic properties. Many crop plants provide an array of minerals, vitamins, and antioxidant-rich bioactive phytochemicals. Increasing incidences of chronic diseases such as cancer, diabetes and HIV, and malnutrition necessitate global attention to health and nutrition security with equal emphasis to food security. This compendium compiles results of researches on biochemical, physiological and genetic mechanisms underlying biosynthesis of the health and nutrition related nutraceuticals. It also explores the precise breeding strategies for augmentation of their content and amelioration of their quality in crop plants under all commodity categories including cereals and millets, oilseeds, pulses, fruits and nuts, and vegetables. The compendium comprise 5 sections dedicated to these 5 commodity groups and presents enumeration on the concepts, strategies, tools and techniques of nutraceutomics. These sections include 50 chapters devoted to even number of major crop plants. These chapters present deliberations on the biochemistry and medicinal properties of the nutracuticals contained; genetic variation in their contents; classical genetics and breeding for their quantitative and qualitative improvement; tissue culture and genetic engineering for augmentation of productivity and quality; and sources of genes underlying their biosynthesis. They also include comprehensive enumeration on genetic mapping of the genes and QTLs controlling the contents and profile of the nutraceuticals and molecular breeding for their further improvement through marker assisted selection and backcross breeding tools. Prospects of post-genomic precise breeding strategies including genome-wide association mapping, genomic selection, allele mining, and genome editing are also discussed. This compendium fills the gap in academia, and research and development wings of the private sector industries interested in an array of subjects including genetics, genomics, tissue culture, genetic engineering, molecular breeding, genomics-assisted breeding, bioinformatics, biochemistry, physiology, pathology, entomology, pharmacognosy, IPR, etc., and will also facilitate understanding of the policy making agencies and people in the socio-economic domain and research sponsoring agencies.

Free Download Applications of Genome Engineering in Plants
by Upadhyay, Santosh Kumar;
English | 2024 | ISBN: 1394183887 | 448 pages | True PDF | 5.84 MB

Free Download The Topological Model of Genome and Evolution: Understanding the Origin and Nature of Life
English | 2023 | ISBN: 9819943175 | 1003 Pages | PDF EPUB (True) | 20 MB
This book deals with the missing link in the domain of functional genomics viz. genomic architecture. It begins with a deconstruction of the Darwinian paradigm using the proposed model of modified involuted manifolds. It recasts the process of natural selection as a process of information transfer. Using a topological model, this book outlines a new genomic architecture. The key argument for this proposed model is that some such structuralism has always been implicit in genomics. The proposed model fits very well with the known genomic characteristics and allows to separate the regulatory genome from the transcriptive genomes. The model is capable of discerning modular architecture of genomes with different genomic functionalities existing in hierarchical relationships and demonstrates that genomes act as units of selection and as the environment for the individual genes which act as competing species. Towards the end, the book also examines the role of genomic evolution in cancer and the principles of natural selection and evolution of the genotype. The regulatory genome is also discussed, with an emphasis on its evolution and natural selection. It is a valuable source for researchers working in functional genomics, mathematical modeling in biology and evolutionary genomics.

Free Download The Topological Model of Genome and Evolution: Understanding the Origin and Nature of Life
English | 2023 | ISBN: 9819943175 | 1003 Pages | PDF EPUB (True) | 20 MB
This book deals with the missing link in the domain of functional genomics viz. genomic architecture. It begins with a deconstruction of the Darwinian paradigm using the proposed model of modified involuted manifolds. It recasts the process of natural selection as a process of information transfer. Using a topological model, this book outlines a new genomic architecture. The key argument for this proposed model is that some such structuralism has always been implicit in genomics. The proposed model fits very well with the known genomic characteristics and allows to separate the regulatory genome from the transcriptive genomes. The model is capable of discerning modular architecture of genomes with different genomic functionalities existing in hierarchical relationships and demonstrates that genomes act as units of selection and as the environment for the individual genes which act as competing species. Towards the end, the book also examines the role of genomic evolution in cancer and the principles of natural selection and evolution of the genotype. The regulatory genome is also discussed, with an emphasis on its evolution and natural selection. It is a valuable source for researchers working in functional genomics, mathematical modeling in biology and evolutionary genomics.

Free Download Personal Genome Medicine: The Legal and Regulatory Transformation of US Medicine
English | 2023 | ISBN: 100929332X | 479 Pages | PDF | 3 MB
In the years following FDA approval of direct-to-consumer, genetic-health-risk testing, millions of people in the United States have sent their DNA to companies to receive personal genetic health risk information without physician or other learned medical professional involvement. In Personal Genome Medicine, Michael J. Malinowski examines the ethical, legal, and social implications of this development. Drawing from the past and present of medicine in the U.S., Malinowski applies law, policy, public and private sector practices, and governing norms to analyze the commercial personal genome sequencing and testing sectors and to assess their impact on the future of U.S. medicine. Written in relatable and accessible language, the book also proposes regulatory reforms for government and medical professionals that will enable technological advancements while maintaining personal and public health standards.

Free Download The Watermelon Genome by Sudip Kr. Dutta, Padma Nimmakayala, Umesh K. Reddy
English | PDF (True) | 2023 | 175 Pages | ISBN : 3031347153 | 4.6 MB
This book is the first comprehensive compilation of deliberations on botany, genetic resources and diversity, classical genetics and traditional breeding, genetic transformation, and detailed enumeration on molecular maps and mapping of economic genes and QTLs, whole genome sequencing and comparative genomics in watermelon, and elucidation on functional genomics. The genomic resources for disease resistance, genomics of fruit and quality traits of watermelon, and molecular and metabolic regulation of nutraceuticals in watermelon are discussed. Mapping of quality traits, and biotic and abiotic resistance is also to be discussed. The genome draft of watermelon and application of genome editing are covered. The book contains approximately 250 pages and over 10 chapters authored by globally reputed experts on the relevant field in this crop. This book is useful to the students, teachers, and scientists in academia and relevant private companies interested in horticulture, genetics, breeding, pathology, entomology, physiology, molecular genetics and genomics, in vitro culture and genetic engineering, and structural and functional genomics. This book is also useful for seed industries

Free Download Genome Editing in Biomedical Sciences
English | 2023 | ISBN: 3031333241 | 397 Pages | PDF EPUB (True) | 11 MB
This volume focuses on applying the Crispr system in editing the genome of human cells (in vitro and in vivo) and model organisms used in biomedical research. With the advent of Crispr technology, genome editing soon became a procedure of great interest to laboratories worldwide due to its relative ease and accuracy. In biomedical sciences, genome editing by Crispr has already enabled the development of new experimental model systems. In medicine, therapeutic alternatives for the genetic "correction" of diseases have already begun to appear. Therefore, the book’s purpose is to bring in a single volume, chapters that show the scientific community in biomedicine, medicine, human genetics, oncology, virology, and parasitology, among others, the advances in genomic editing. In a chapter dedicated to the ethical aspects of human genomic editing, we also address what we can and should do with this (bio)technology. The book chapters were written by productive researchers specializing in Crispr genome editing. The chapters cover the concept of Crispr and genome editing and how to use this new methodology in biomedical research and medicine, among other aspects, including the ethical controversy around its use in humans. The writing of the chapters keeps a specialized language intelligible enough for those who want to introduce themselves to the subject.

Free Download The Almond Tree Genome
English | 2023 | ISBN: 3030303012 | 405 Pages | PDF EPUB (True) | 31 MB
This book brings together the latest information on almond genomics and transcriptomics, with a particular focus on cutting-edge findings, tools, and strategies employed in genome sequencing and analysis with regard to the most important agronomic traits.