Tag: Drug

Women’s Drug Use in Everyday Life


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English | 2024 | ISBN: 3031460561 | 352 Pages | PDF EPUB (True) | 4.4 MB
This open access book explores the increasing role of psychoactive substances in contemporary everyday life, focussing on women’s use. Drawing on an ethnographic study in Sweden, it uses cultural studies and queer phenomenology to analyse the women’s narratives of drug use relating to themes that encompass social, legal, cultural, embodied and gendered perspectives on drugs in the contemporary Western world. It examines topics such as stigma, happiness, children, the body, gifts, the drug market, medication, sickness and health and also the orientation of themselves towards others, to social and cultural norms, to drug laws and to the substances. It discusses how drug related spaces and directions be analysed in terms of gender and class, and how, in turn, the directions of contemporary society and culture can be affected by drug use. It speaks to academics in Sociology, Criminology, Ethnology, Gender studies, Law and History.

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Natural Product-based Synthetic Drug Molecules in Alzheimer’s Disease


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English | 2023 | ISBN: 9819960371 | 794 Pages | PDF EPUB (True) | 37 MB
This book illustrates the importance of natural products as the source for the development of novel drugs for the treatment of neurodegenerative disorders, including Alzheimer’s disease. It also highlights the role of reactive oxygen species and altered metal homeostasis in the progression of Alzheimer’s disease and examines the potential of antioxidants and anti-chelating agents in the clinical intervention of neurodegenerative diseases. The book also discusses the role of neuroinflammation in the pathogenesis of Alzheimer’s disease. The chapters provide information about the drug targets, progress in the development of natural product-based therapeutics, biomarkers, fluorescent diagnostic tools, and theranostic for Alzheimer’s disease. The book also provides information about the design and synthesis of natural product-based derivatives against the various targets of Alzheimer’s disease including epigenetic targets and the metal dyshomeostasis hypothesis. Cutting across different disciplines, this book is a valuable source for neuroscientists, chemical biologists, pharmaceutical researchers, and synthetic biologists.

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Natural Product Based Drug Discovery Against Human Parasites


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English | 2023 | ISBN: 9811996040 | 1034 Pages | PDF EPUB (True) | 52 MB
This book comprehensively reviews current and novel treatment strategies against human parasites, including protozoans and helminths, using natural products. The initial chapters summarize the conventional treatment strategies and natural-product based therapeutics against these parasites. It discusses biochemical tools and techniques for the discovery of natural product based drugs against human parasites. The book also covers the ingenious and innovative mechanisms to achieve drug resistance by the protozoan parasites and strategies to overcome the resistance. It entails mechanistic insight into the modulation of host immune responses to delay or inhibit parasite clearance and explores host-pathogen interactions that mediate immunity against subsequent parasite challenge. In turn, the volume helps in understanding the immunobiology of the parasites and tools to identify candidate vaccine antigens and novel delivery systems against the protozoan parasites. Lastly, it explores the role of advanced methods, including nanotechnology, marine bioprospecting, and microorganisms-derived biochemicals against the protozoan parasites.

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Nanotechnology and Drug Delivery Principles and Applications


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English | 2024 | ISBN: 9814968838 | 646 Pages | PDF (True) | 28 MB
This book presents an overview of the rapidly developing field of nanotechnology applications in drug delivery systems and covers a variety of technologies and materials that help in achieving vast variation in the particle size needed in technology and drug delivery-based research. It discusses nanotechnology’s use in healthcare for the development of target-specific drug therapy and smart field systems and in the pharmaceutical industry to improve the quality, efficacy, and shelf life of medicines. Bringing together principles, theory, practice, and applications of nanotechnology, the book is a useful resource for chemists, physicists, biomedical researchers, engineers, advanced undergraduate and graduate-level students in nanotechnology, researchers in pharmaceutical sciences, chemistry, biology, biotechnology engineering, and general readers in nanotechnology.

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Exploring Drug Delivery to the Peritoneum


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English | 2023 | ISBN: 3031316932 | 453 Pages | PDF EPUB (True) | 28 MB
The Peritoneal cavity (PC) is the key metastatic site for intra-abdominal malignancies (e.g., GI tract and rectal cancer). PC sites can be used to target several other diseases where lymphatic drug delivery is desired without dumping large amounts of the drug. Till recently, it was thought that treatment with curative intent was impossible but that was challenged by the introduction of cytoreductive surgery (CRS) and heated intraperitoneal chemotherapy (HIPEC), and PIPAC (pressurized intraperitoneal aerosol chemotherapy). Recently, a growing number of preclinical and clinical studies advocate intraperitoneal (IP) chemotherapy as an alternative post-operative therapy for cancer. Although their effectiveness has been proven both experimentally and clinically, there is still little understanding of the role of drug delivery systems (DDS) in targeting drugs in the intraperitoneal (IP) cavity.

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Clinical Applications of Mass Spectrometry in Drug Analysis, 2nd Edition


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English | 2024 | ISBN: 1071635409 | 744 Pages | PDF EPUB (True) | 33 MB
This fully updated volume describes methods and protocols for a number of drugs and toxins in a stepwise manner. Exploring the versatility and flexibility of mass spectrometry, the book covers the advantages of this technology, which typically include elimination of the need for special reagents such as antibodies, increased sensitivity and specificity, and multi-component analysis enabling the screening of tens to hundreds of compounds in a single assay run. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, as well as tips on troubleshooting and avoiding known pitfalls.

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The Oxford Handbook of Global Drug History (Oxford Handbooks)


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English | March 25, 2022 | ISBN: 0190842644 | 720 pages | MOBI | 3.10 Mb
Drugs and their illicit use have long fascinated writers and the public at large. Informed by new interdisciplinary perspectives, a growing number of academically trained historians are now approaching drugs as a wide-open topic for serious research. This Handbook of Global Drug History is the first major attempt by historians of drugs to take stock of the recent progress and directions of this field, utilizing both a global scope and long-term historical perspective. Thirty-five original essays simultaneously survey what is known historically about drugs across the world (in Europe, the Americas, Asia, and Africa) as well as illustrating their historical interconnections.

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Novel Technologies in Biosystems, Biomedical & Drug Delivery


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English | 2023 | ISBN: 9819952808 | 506 Pages | PDF EPUB (True) | 20 MB
The book gives an insight into the theoretical background, conceptual understanding, latest developments, and applications in the field of pharmaceuticals in general and drug design, discovery, biosystems, and biomedical and drug delivery technologies in particular. Knowledge is drawn from various disciplines such as Chemistry, Biology, Material Science and Engineering, Statistics, Biomedicine, and Genetics . A host of applications like bio-imaging, novel biological agents, testing, characterization and validation of drugs, computer-based models in drug design, and application of statistical tools in data analysis, design, and development of drug delivery systems, and ecosystems are dealt with in detail. The said book undoubtedly confirms the requirements of the postgraduate students, research scholars, academicians, scientists, and researchers from the academia, pharmaceutical, biotechnology, and chemical engineering domain. The book covers a conceptual understanding of the exploration of drugs in tandem with intended uses, sound ecosystem development, and carriers for drug and supplement delivery.

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