Tag: Model

The Topological Model of Genome and Evolution


Free Download The Topological Model of Genome and Evolution: Understanding the Origin and Nature of Life
English | 2023 | ISBN: 9819943175 | 1003 Pages | PDF EPUB (True) | 20 MB
This book deals with the missing link in the domain of functional genomics viz. genomic architecture. It begins with a deconstruction of the Darwinian paradigm using the proposed model of modified involuted manifolds. It recasts the process of natural selection as a process of information transfer. Using a topological model, this book outlines a new genomic architecture. The key argument for this proposed model is that some such structuralism has always been implicit in genomics. The proposed model fits very well with the known genomic characteristics and allows to separate the regulatory genome from the transcriptive genomes. The model is capable of discerning modular architecture of genomes with different genomic functionalities existing in hierarchical relationships and demonstrates that genomes act as units of selection and as the environment for the individual genes which act as competing species. Towards the end, the book also examines the role of genomic evolution in cancer and the principles of natural selection and evolution of the genotype. The regulatory genome is also discussed, with an emphasis on its evolution and natural selection. It is a valuable source for researchers working in functional genomics, mathematical modeling in biology and evolutionary genomics.

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The Topological Model of Genome and Evolution


Free Download The Topological Model of Genome and Evolution: Understanding the Origin and Nature of Life
English | 2023 | ISBN: 9819943175 | 1003 Pages | PDF EPUB (True) | 20 MB
This book deals with the missing link in the domain of functional genomics viz. genomic architecture. It begins with a deconstruction of the Darwinian paradigm using the proposed model of modified involuted manifolds. It recasts the process of natural selection as a process of information transfer. Using a topological model, this book outlines a new genomic architecture. The key argument for this proposed model is that some such structuralism has always been implicit in genomics. The proposed model fits very well with the known genomic characteristics and allows to separate the regulatory genome from the transcriptive genomes. The model is capable of discerning modular architecture of genomes with different genomic functionalities existing in hierarchical relationships and demonstrates that genomes act as units of selection and as the environment for the individual genes which act as competing species. Towards the end, the book also examines the role of genomic evolution in cancer and the principles of natural selection and evolution of the genotype. The regulatory genome is also discussed, with an emphasis on its evolution and natural selection. It is a valuable source for researchers working in functional genomics, mathematical modeling in biology and evolutionary genomics.

(more…)

Streaming Data Mesh A Model for Optimizing Real-Time Data Services


Free Download Streaming Data Mesh: A Model for Optimizing Real-Time Data Services by Hubert Dulay, Stephen Mooney
English | June 20, 2023 | ISBN: 1098130723 | 223 pages | MOBI | 7.63 Mb
Data lakes and warehouses have become increasingly fragile, costly, and difficult to maintain as data gets bigger and moves faster. Data meshes can help your organization decentralize data, giving ownership back to the engineers who produced it. This book provides a concise yet comprehensive overview of data mesh patterns for streaming and real-time data services.

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Model-Based Inquiry in Biology Three-Dimensional Instructional Units for Grades 9-12


Free Download Model-Based Inquiry in Biology: Three-Dimensional Instructional Units for Grades 9-12 by Ron Gray, Todd Campbell
English | April 10, 2023 | ISBN: 168140673X | 420 pages | PDF | 10 Mb
You shouldn’t have to scavenge for high-quality curriculum materials that both center around real-world phenomena and align with A Framework for K-12 Science Education and the Next Generation Science Standards. And now you don’t have to-thanks to Model-Based Inquiry in Biology: Three-Dimensional Instructional Units for Grades 9-12. This book will help you engage your biology students in constructing, critiquing, revising, and testing models to explain how things happen in the world. The book is divided into two parts: Section 1 introduces model-based inquiry (MBI) and the ideas that frame it. Section 2 contains four complete MBI biology units. All come with the background, examples, and guidance you need to lead students to their final evidence-based explanations of the phenomena that anchor each unit. The units cover four areas: molecules and organisms, ecosystems, heredity, and biological evolution. The curriculum builds strategically from unit to unit and integrates disciplinary core ideas, crosscutting concepts, and science and engineering practices. The authors-experts in model-based teaching and learning-tested each unit in actual classrooms. They make it clear that by using modeling to explain events, you can shift the emphasis of your biology lessons away from "we need to learn about this topic in order to do well in class" to "we need to figure out why or how something happens." Model-Based Inquiry in Biology will help you to create meaningful learning experiences for your students as they strive to make sense of the world around them.

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