Tag: Signaling

ROS Signaling in Plants


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English | 2024 | ISBN: 1071638254 | 267 Pages | PDF (True) | 6.3 MB
This detailed volume presents methodologies for studying reactive oxygen species (ROS) metabolism in plant cells, including techniques for detecting different types of ROS such as superoxide radicals, hydrogen peroxide or singlet oxygen, as well as ROS generating systems such as xanthine oxidoreductase. The book provides alternatives to determine malondialdehyde, electrochemical detection approaches for determining total antioxidant capacity (TAC) as well as enzymatic antioxidants, as well as methods for studying non-enzymatic antioxidants and some components of the secondary metabolism. Written for the highly successful Methods in Molecular Biology series, the chapters in this book provide the kind of detailed implementation advice that leads to ideal results in the laboratory.

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Virtue Signaling Essays on Darwinian Politics & Free Speech


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2019 | 201 Pages | ISBN: 1951555066 | EPUB | 3 MB
‘Virtue signaling’ is the phrase that got popular on social media during the 2016 election as a way of derogating political opponents. But what is virtue signaling, really? How does it work, where does it come from, and is it really a bad thing? How can it help people to virtue signaling better — when you’re doing it, and when your friends, family, colleagues, and mates are doing it?This short, thoughtful, easy-to-read book is about how we can better understand people’s instincts to show off our moral virtues, personality traits, ideologies, political attitudes, and lifestyle choices through our public behavior and language, from dating to street protests to social media to academic censorship. It shows how virtue signaling is the key to understanding current debates about free speech and viewpoint diversity on campuses, in corporations, and throughout society.Understanding virtue signaling is a social superpower, like understanding body language, or personality traits, or sex differences. Are you curious why politics and religion lead to so many bitter debates around the Thanksgiving dinner table — even among relatives who get along in every other domain? Or why so many single people put ‘No Trump supporters!’ or ‘No Libtards!’ on the dating profiles — when politics plays such a small role in day-to-day relationships? Or why Gen Z college students want to censor ideas they think are evil — when they’re supposed to be exposing themselves to diverse perspectives?Virtue signaling is one of those concepts that’s easy to understand, but that most people don’t bother to face — because we’re all doing it all the time, and acknowledging our own virtue signaling makes us feel embarrassed and hypocritical.Let’s face the reality of virtue signaling.This book offers a scientifically grounded, practical, non-partisan set of insights so you understand your own ideological passions, your relationships, and your society much more easily. If you don’t understand your own virtue signaling, then your ideologies and signaling habits, not your conscious mind, are running your life. If you don’t understand other people’s virtue signaling, then it’s hard to take their point of view and to find common ground with them. If you don’t understanding virtue signaling in the political realm, it’s hard to convince other citizens to support your causes, policies, and candidates.This book collects seven essays written from 1996 through 2018. They’re all focused around the evolutionary psychology of politics, ethics, and language. It includes a new preface, new introductions that give the backstory to each essay, and a new list of further readings (including about 100 books by other people).The book is about 32,000 words, or about 85-130 pages depending on your reader format.

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Insulin Signaling From Cultured Cells to Animal Models


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English | 2002 | ISBN: 0415271746 | 442 Pages | PDF | 14.0 MB
With contributions from the leading researchers in the field, this volume brings together the latest studies on insulin action and signal transduction to provide a state-of-the-art reference for graduate researchers and students in diabetes and endocrinology.

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Signaling Pathways and Molecular Mediators in Metastasis


Free Download Signaling Pathways and Molecular Mediators in Metastasis By Robert B. Den MD, Adam P. Dicker MD, PhD (auth.), Alessandro Fatatis (eds.)
2012 | 378 Pages | ISBN: 9400725574 | PDF | 9 MB
This work presents the most advanced discoveries from translational research laboratories directly involved in identifying molecules and signalling pathways that play an instrumental role in metastasis. In contrast to other works, conventionally focused on a single type of tumour, the various chapters in this book provide a broad perspective of the similarities and discrepancies among the dissemination of several solid malignancies. Through recurrent and overlapping references to molecular mechanisms and mediators, the readers will gain knowledge of the common ground in metastasis from a single source. Finally, an introductory chapter provides a clinical perspective of the problems presented by metastatic tumours for diagnosis and treatment. The work presented here is directed to researchers in tumour biology with a developing interest in metastatic dissemination as well as medical and graduate students seeking to expand and integrate the notions acquired in basic cancer biology and oncology courses.

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Role of Signaling Pathways in Brain Tumorigenesis


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English | 2023 | ISBN: 9811584729 | 378 Pages | PDF EPUB (True) | 21 MB
This book provides acomprehensive overview of cell signalling pathways and morphogens in the genesis of brain tumours. It also explains the role of brain tumour stem cells in the brain tumour progression. It also elucidates the novel early biomarkers that can be utilized to diagnose brain tumours. It presents the basic developmental pathways and morphogens, including retinoic acid and TGF-b that promote brain tumorigenesis. The chapters illustrate the role of stem cells and stem cells mediated cell signalling pathways including, Sonic hedgehog, Notch, Wnt in the brain tumour growth. The chapters also emphasize the role of transcription factors, mainlyNanog, Sox, BMI1, HIF1 and Pax6 in the brain tumouriogensis. It highlights the role of NF-kb, Myc and neurotrophins in the brain tumour development. Finally, the book summarizes the potential early therapeutic targets and targeted drug discovery for brain tumours.

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Gasotransmitters Signaling in Plants under Challenging Environment


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English | 2023 | ISBN: 303143028X | 622 Pages | PDF EPUB (True) | 23 MB
Abiotic stressors, such as drought, extreme temperatures, heavy metals, or high salinity, are causing huge crop losses worldwide. These abiotic stressors are expected to become more extreme, less predictable, and more widespread in the near future. The harm of abiotic stresses includes the disruption of cellular redox homeostasis, reactive oxygen species (ROS) production, and oxidative stress in the plant. Plants have different mechanisms to fight stress, and these mechanisms are responsible for maintaining the required homeostasis in plants. Research on gasotransmitters is rapidly expanding and knowledge regarding the potential of gasotransmitters in biology and medicine is accumulating. Over the past few decades, the roles of these signaling molecules, especially NO and H2S, have been extensively studied for their application in plants. Recently, the emissions of endogenous gasotransmitters in plants have been widely studied and analyzed, thereby providing information to facilitate our understanding of new gasotransmitters signaling pathways. Given the multidimensional role of these signaling molecules, research over the past decades in mitigating abiotic stresses in plant biology and from an agriculture point of view, we intend to bring forth a comprehensive volume "Gasotransmitters Signaling in Plants under Challenging Environment". We are hopeful that this comprehensive volume will furnish the requisite of all those who are working or have an interest in the proposed topic

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Alternate Programmed Cell Death Signaling in Antiviral Host Defense


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English | 2024 | ISBN: 3031452771 | 341 Pages | PDF EPUB (True) | 8 MB
This volume provides a comprehensive review of programmed cell death pathways and their fundamental role in antiviral host defense. The book deep-dives into the molecular functions and regulation of necroptosis and discusses how viruses induce and manipulate this potent innate cellular sensing system.

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Signaling Pathways of the Immune System


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by Frank Columbus

English | 2023 | ISBN: 979-8886976038 | 184 pages | True PDF | 43.48 MB
"This book examines the issue of immunity with the signaling pathways it is associated with, which has come to the fore again with the COVID-19 pandemic. Our book provides an opportunity to have an overview of the signaling pathways involved in the function of cells in the immune system with the latest developments and recent studies on the subject to the reader"-

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